She has been deaf since she was 18 months old. She is the only deaf performer to win the Academy Award for Best Actress in a Leading Role, which she won for Children of a Lesser God at the age of 21.
These famous folks all have something in common . . . an imperfection, a defect or deformity. Some noticeable, some not so much. The main thing they have in common is they never let it stand in the way of success.